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Article

DNA methylation assay based on pyrosequencing for determination of smoking status

29 Jun 2018

Abstract excerpt

The goal of this study was to utilize pyrosequencing to identify CpG sites indicative of tobacco smoking using DNA sequences surrounding ten frequently reported smoking-related CpGs. Initially, six genetic loci were investigated including AHRR, 2q37, 6p21.33, GFI1, F2RL3, and MYO1G in order to detect novel CpG sites associated with tobacco smoking. The methylation data revealed a set of 23 consecutive CpG sites...

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Share to Epigenetics and DNA Methylation
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PMID: 29956353
DOI: 10.1002/elps.201800098

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