Article
Characterization of yeast U1 snRNP A protein: identification of the N-terminal RNA binding domain (RBD) binding site and evidence that the C-terminal RBD functions in splicing.
RNA (New York, N.Y.) - 1 Oct 1996
Tang J, Rosbash M
Abstract excerpt
The yeast U1A protein is a U1 snRNP-specific protein. Like its human counterpart (hU1A), it has two conserved RNA binding domains (RBDs). The N-terminal RBD is quite different from the human protein, and a binding site on yeast U1 snRNA is not readily apparent. The C-terminal RBD is of unknown fu...
Topics
- Alkylating Agents
- Amino Acid Sequence
- Base Sequence
- Binding Sites
- Fungal Proteins
- Genes, Fungal
- Genes, Lethal
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- RNA Precursors
- RNA Splicing
- RNA, Fungal
- RNA-Binding Proteins
- Ribonucleoprotein, U1 Small Nuclear
- Saccharomyces cerevisiae
- Sulfuric Acid Esters