Requirement of U12 snRNA for in vivo splicing of a minor class of eukaryotic nuclear pre-mRNA introns.

doi:10.1126/science.271.5256.1716

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Article

Requirement of U12 snRNA for in vivo splicing of a minor class of eukaryotic nuclear pre-mRNA introns.

Science (New York, N.Y.) - 22 Mar 1996

Hall S L, Padgett R A

Abstract excerpt

A conserved sequence element in a minor class of eukaryotic pre-messenger RNA (pre-mRNA) introns was previously proposed to base pair with a complementary sequence in the U12 small nuclear RNA (snRNA) in a manner analogous to the pairing of US snRNA with the branch site sequence of the major clas...

Topics

Animals
Base Composition
Base Sequence
CHO Cells
Conserved Sequence
Cricetinae
Genetic Vectors
Humans
Introns
Molecular Sequence Data
Mutation
Nucleic Acid Conformation
RNA Precursors
RNA Splicing
RNA, Small Nuclear

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