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Article

A human immunodeficiency virus type 1-infected individual with low viral load harbors a virus variant that exhibits an in vitro RNA dimerization defect.

Journal of virology - 1 May 2004

Huthoff Hendrik, Das Atze T, Vink Monique, Klaver Bep, Zorgdrager Fokla, Cornelissen Marion, Berkhout Ben

Abstract excerpt

We investigated the in vitro RNA dimerization properties of the untranslated leader RNA derived from human immunodeficiency virus type 1 variants circulating in an individual with a low viral load and slow disease progression. The leader sequences of these viruses contain highly unusual polymorphisms within the dimerization initiation site (DIS): an insert that abolishes dimerization and a compensatory...

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Identifiers

PMID: 15078972
DOI: 10.1128/jvi.78.9.4907-4913.2004
PMCID: PMC387700

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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