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A 19-Nucleotide Sequence Upstream of the 5' Major Splice Donor Is Part of the Dimerization Domain of Human Immunodeficiency Virus 1 Genomic RNA

15 Nov 1994

Abstract excerpt

The genome of all retroviruses, including human immunodeficiency virus type 1 (HIV-1), consists of two identical RNAs noncovalently linked near their 5' end. Dimerization of genomic RNA is thought to modulate several steps in the retroviral life cycle, such as recombination, translation, and encapsidation. We report the results of experiments designed to identify the 5' and 3' boundaries of the dimerization...

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PMID: 7947755
DOI: 10.1021/bi00249a035

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A 19-Nucleotide Sequence Upstream of the 5' Major Splice Donor Is Part of the Dimerization Domain of Human Immunodeficiency Virus 1 Genomic RNAPMID 7947755Read ↗

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