Article
Aberrant promoter methylation in overexpression of CITED1 in papillary thyroid cancer.
Thyroid : official journal of the American Thyroid Association - 1 May 2011
Sassa Miho, Hayashi Yoshitaka, Watanabe Reiko, Kikumori Toyone, Imai Tsuneo, Kurebayashi Junichi, Kiuchi Tetsuya, Murata Yoshiharu
Abstract excerpt
BACKGROUND: More than 80% of all thyroid cancers, the most common endocrine malignancy, are papillary thyroid cancer (PTC). It is well established that CITED1 (Cbp/p300 Interacting Transactivators with glutamic acid [E] and aspartic acid [D]-rich C-terminal domain) mRNA is characteristically overexpressed in PTC. Our previous study suggested a positive association of BRAF mutation with CITED1 overexpression....
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