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Article

DNA methylation of MAPK signal-inhibiting genes in papillary thyroid carcinoma.

Anticancer research - 1 Nov 2013

Lee Eun Kyung, Chung Ki-Wook, Yang Sun Kyung, Park Min Ji, Min Hye Sook, Kim Seok Won, Kang Han Sung

Abstract excerpt

BACKGROUND: The purpose of this study was to identify the DNA methylation status of the mitogen-activated protein kinase (MAPK) signal-inhibiting genes dual-specificity phosphatase 4 (DUSP4) and 6 (DUSP6); and serpin peptidase inhibitor A member 5 (SERPINA5) in thyroid cancer. MATERIALS AND METHODS: Using 76 papillary thyroid cancer(PTC) tissues and three thyroid cancer cell lines (TPC1, WRO82-1 and XTC), the...

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Share to Carcinoma, Papillary
Share to Dual-Specificity Phosphatases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mitogen-Activated Protein Kinases

Share to Neoplasm Staging

Share to Proto-Oncogene Proteins B-raf

Share to Thyroid Gland

Share to Thyroid Neoplasms

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 24222120

Genes

SERPINA5
BRAF
DUSP4
DUSP6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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