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Article

Expression of CD45 isoforms by fresh and activated human gamma delta T lymphocytes and natural killer cells.

International immunology - 1 Jul 1991

Braakman E, Sturm E, Vijverberg K, van Krimpen B A, Gratama J W, Bolhuis R L

Abstract excerpt

Naive and primed alpha beta T cells can be distinguished on the basis of their differential expression of CD45RA and CD45RO, respectively. The present study indicates that these CD45-isoforms also identify naive and primed maturational stages of gamma delta T cells and natural killer (NK) cells. In peripheral blood, all V gamma 9-V delta 2 gamma delta T cells reportedly express CD45RO whereas all V delta gamma...

Topics

Antigens, CD
Histocompatibility Antigens
Humans
In Vitro Techniques
Killer Cells, Natural
Leukocyte Common Antigens
Lymphocyte Activation
Phenotype
Receptors, Antigen, T-Cell, gamma-delta
T-Lymphocyte Subsets

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1832950
DOI: 10.1093/intimm/3.7.691

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1832950-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Expression of CD45 isoforms by fresh and activated human gamma delta T lymphocytes and natural killer cells.PMID 1832950Read ↗

Human naive T cells activated by cytokines differentiate into a split phenotype with functional features intermediate between naive and memory T cells.Semantic proximity Read ↗

Phenotypic comparison of the three populations of human lymphocytes defined by CD45RO and CD45RA expression.Semantic proximity Read ↗

CD45 Isoform Profile Identifies Natural Killer (NK) Subsets with Differential ActivitySemantic proximity Read ↗

Phenotypic changes and proliferative activity of human gamma delta T cell receptor-bearing cells upon activation.Semantic proximity Read ↗

Differential interleukin secretion by in vitro activated human CD45RA and CD45RO CD4+ T cell subsets.Semantic proximity Read ↗

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