Phenotypic comparison of the three populations of human lymphocytes defined by CD45RO and CD45RA expression.

Abstract excerpt

Published reports indicate that CD45RO-CD45RAbright T cells are native T cells, CD45RObrightCD45RA- T cells are memory T cells, and that concomitant loss of CD45RA expression and gain of CD45RO expression occurs during transition from naive to memory status. Thus, following in vitro activation of CD45RO- CD45RAbright T cells, a subset of transitional CD45ROdimCD45RAdim T cells is observed before conversion to a...

Topics

• Humans
• Immunologic Memory
• Leukocyte Common Antigens
• Lymphocyte Activation
• Phenotype
• Receptors, Interleukin-2
• T-Lymphocyte Subsets