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Article

Rapid conversion of naive to effector T cell function counteracts diminished primary human newborn T cell responses.

Clinical and experimental immunology - 1 Jun 1999

Early E, Reen D J

Abstract excerpt

The reduced incidence of graft versus host disease following the use of human cord blood as a source of stem cells for bone marrow reconstitution challenges our understanding of the immunocompetence of newborn T cells. Newborn CD4+ T cells express mainly the CD45RA phenotype and have been considered to respond comparably to adult CD4+ T cells exhibiting the CD45RA phenotype. We compared the in vitro kinetics of...

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Identifiers

PMID: 10361246
DOI: 10.1046/j.1365-2249.1999.00920.x
PMCID: PMC1905313

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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