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Article

Association of CHRNA4 polymorphisms with smoking behavior in two populations.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jun 2011

Han Shizhong, Yang Bao-Zhu, Kranzler Henry R, Oslin David, Anton Raymond, Gelernter Joel

Abstract excerpt

CHRNA4, the gene that encodes the nicotinic acetylcholine receptor α(4) subunit, is a potential candidate gene for nicotine dependence (ND). However, studies of the association of CHNRA4 with smoking behavior have shown inconsistent results. Our meta-analysis of linkage studies of smoking behavior identified a genome-wide significant linkage of the phenotype maximum number of cigarettes smoked in a 24-hour period...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Linkage Disequilibrium

Share to Polymorphism, Single Nucleotide

Share to Receptors, Nicotinic

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Source

Open in PubMed Open full text

Identifiers

PMID: 21445957
DOI: 10.1002/ajmg.b.31177
PMCID: PMC3742073

Genes

CHRNA4
CPD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Association of CHRNA4 polymorphisms with smoking behavior in two populations.PMID 21445957Read ↗

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