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Article

CHRNA4 and tobacco dependence: from gene regulation to treatment outcome.

Archives of general psychiatry - 1 Sept 2007

Hutchison Kent E, Allen David L, Filbey Francesca M, Jepson Christopher, Lerman Caryn, Benowitz Neal L, Stitzel Jerry, Bryan Angela, McGeary John, Haughey Heather M

Abstract excerpt

CONTEXT: Given the probable importance of the alpha4 subunit of the neuronal nicotinic acetylcholine receptor, the gene that codes for this subunit (CHRNA4) represents an excellent starting point for a genetic investigation of smoking behavior. OBJECTIVE: To achieve a better understanding of the role of this gene in the cause and treatment of tobacco dependence, we adopted a transdisciplinary pharmacogenetic...

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Source

Identifiers

PMID: 17768273
DOI: 10.1001/archpsyc.64.9.1078

Genes

CHRNA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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CHRNA4 and tobacco dependence: from gene regulation to treatment outcome.PMID 17768273Read ↗

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