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Article

Demonstration of a splenic cytotoxic effector cell in mice of genotype SCID/SCID.BG/BG.

Cellular immunology - 1 Oct 1990

MacDougall J R, Croy B A, Chapeau C, Clark D A

Abstract excerpt

Splenocytes from mice of genotype scid/scid.bg/bg were tested in vitro to characterize the nature of the immunological deficit in these doubly mutant animals. The cells were unresponsive to the mitogens LPS and Con A and to alloantigens, as predicted for scid/scid genotype. Splenocytes from scid/scid.bg/bg lysed the NK cell-sensitive target cell line YAC at levels approximately 50% lower than those observed for...

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Identifiers

PMID: 2144467
DOI: 10.1016/0008-8749(90)90165-n

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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