Syngeneic B lymphoma cells provide a unique stimulus to natural killer (NK) cells in genetically low-NK SJL/J mice.

Abstract excerpt

SJL/J mice are a genetically low-NK strain, and their cytotoxic activity cannot be augmented with conventional NK inducers. In contrast, effector cells taken from the lymphoid tissues of SJL mice bearing a syngeneic B cell lymphoma (RCS) show variable, but significant levels of cytotoxic activity against NK-susceptible targets, such as YAC-1. Previous results suggested that the RCS cells themselves contributed to...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cytotoxicity, Immunologic
• Share to H-2 Antigens
• Share to Histocompatibility Antigens Class II