Article
Disparate effect of beige mutation on cytotoxic function between natural killer and natural killer T cells.
Immunology - 1 Jun 2000
Bannai M, Oya H, Kawamura T, Naito T, Shimizu T, Kawamura H, Miyaji C, Watanabe H, Hatakeyama K, Abo T
Abstract excerpt
Beige mice lack natural killer (NK) cytotoxicity, although NK cells are normally present. In recent studies, NK T cells have been newly identified. We therefore examined the number and function of NK T cells in beige mice. The number of NK T cells was at a normal level in the liver of beige mice. NK cytotoxicity was decreased in the liver of these mice, whereas NK T cytotoxicity was intact. When immunochemical...
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