Association of HLA class I markers with multiple sclerosis in the Italian and UK population: evidence of two independent protective effects.

doi:10.1136/jmg.2010.080721

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Association of HLA class I markers with multiple sclerosis in the Italian and UK population: evidence of two independent protective effects.

Journal of medical genetics - 1 Jul 2011

Bergamaschi Laura, Ban Maria, Barizzone Nadia, Leone Maurizio, Ferrante Daniela, Fasano Maria Edvige, Guerini Franca R, Corrado Lucia, Naldi Paola, Dametto Ennia, Agliardi Cristina, Salvetti Marco, Mechelli Rosella, Galimberti Daniela, Scarpini Elio, Cavalla Paola, Bargiggia Valeria, Caputo Domenico, Cordera Susanna, Monaco Francesco, Momigliano-Richiardi Patricia, D'Alfonso Sandra

Abstract excerpt

BACKGROUND: The association of HLA A*02 with multiple sclerosis (MS) was recently confirmed by the authors, and it was observed that the combined presence of HLA Cw*05 significantly enhanced (threefold) the protective effect of HLA A*02. OBJECTIVES AND METHODS: Since A*02-Cw*05 is carried by two HLA extended haplotypes characterised by the B*4402 and B*1801 alleles, respectively, the association analysis was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Expression Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Order

Share to Genetic Association Studies

Share to Histocompatibility Antigens Class I

Share to HLA-DR Antigens

Share to Italy

Share to Multiple Sclerosis

Share to United Kingdom

Source

Open in PubMed

Identifiers

PMID: 21441263
DOI: 10.1136/jmg.2010.080721

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of HLA class I markers with multiple sclerosis in the Italian and UK population: evidence of two independent protective effects.PMID 21441263Read ↗

HLA-class I markers and multiple sclerosis susceptibility in the Italian population.Semantic proximity Read ↗

Two HLA class I genes independently associated with multiple sclerosis.Semantic proximity Read ↗

HLA-A confers an HLA-DRB1 independent influence on the risk of multiple sclerosis.Semantic proximity Read ↗

Importance of human leukocyte antigen (HLA) class I and II alleles on the risk of multiple sclerosis.Semantic proximity Read ↗

Multiple sclerosis: a modifying influence of HLA class I genes in an HLA class II associated autoimmune disease.Semantic proximity Read ↗

The Involvement of HLA Class II Alleles in Multiple Sclerosis: A Systematic Review with Meta-analysis.Semantic proximity Read ↗

High resolution HLA analysis reveals independent class I haplotypes and amino-acid motifs protective for multiple sclerosis.Semantic proximity Read ↗

Protective role of the HLA-A*02 allele in Portuguese patients with multiple sclerosis.Semantic proximity Read ↗

HLA class II associated risk and protection against multiple sclerosis-a Finnish family study.Semantic proximity Read ↗

Relationship between HLA-DRB1 polymorphism and susceptibility or resistance to multiple sclerosis in Caucasians: a meta-analysis of non-family-based studies.Semantic proximity Read ↗

Genetic dissection of the human leukocyte antigen region by use of haplotypes of Tasmanians with multiple sclerosis.Semantic proximity Read ↗

A major histocompatibility Class I locus contributes to multiple sclerosis susceptibility independently from HLA-DRB1*15:01.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.