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Article

Two HLA class I genes independently associated with multiple sclerosis.

Journal of neuroimmunology - 14 Sept 2010

Link Jenny, Lorentzen Aslaug R, Kockum Ingrid, Duvefelt Kristina, Lie Benedicte A, Celius Elisabeth G, Harbo Hanne F, Hillert Jan, Brynedal Boel

Abstract excerpt

OBJECTIVE: The risk of multiple sclerosis (MS) is influenced by HLA-DRB1, while protective effects have been proposed for HLA-A*02 and HLA-C*05. Our aim was to further understand the role of HLA class I in MS through a comprehensive investigation. METHODS: 1529 MS patients and 1814 controls from Sweden and Norway were genotyped for HLA-DRB1, HLA-A, and HLA-C. Simultaneous analysis of all alleles while adjusting...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20678810
DOI: 10.1016/j.jneuroim.2010.07.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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