Article
HLA class II associated risk and protection against multiple sclerosis-a Finnish family study.
Journal of neuroimmunology - 1 Jan 2002
Laaksonen Mikko, Pastinen Tomi, Sjöroos Minna, Kuokkanen Satu, Ruutiainen Juhani, Sumelahti Marja Liisa, Reijonen Helena, Salonen Reijo, Wikström Juhani, Panelius Martin, Partanen Jukka, Tienari Pentti J, Ilonen Jorma
Abstract excerpt
We analyzed the HLA class II haplotypes in 249 Finnish nuclear families and compared the frequencies of parental haplotypes transmitted or non-transmitted to multiple sclerosis (MS) patients. The most important predisposing haplotype was DRB1*15-DQB1*0602 (P<10(-6)) as expected and a weak predisp...
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