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Article

Association of type 2 diabetes susceptibility genes (TCF7L2, SLC30A8, PCSK1 and PCSK2) and proinsulin conversion in a Chinese population.

Molecular biology reports - 1 Jan 2012

Zheng Xiaoya, Ren Wei, Zhang Suhua, Liu Jingjing, Li Sufang, Li Jinchao, Yang Ping, He Jun, Su Shaochu, Li Ping

Abstract excerpt

TCF7L2 and SLC30A8 have been found to be associated with type 2 diabetes mellitus (T2DM) as well as with impaired proinsulin processing recently, enzymes encoded by PCSK1 and PCSK2 are reported to play an important role in the process of proinsulin conversion. To investigate whether the single nucleotide polymorphisms (SNPs) of TCF7L2, SLC30A8, PCSK1 and PCSK2 were associated with T2DM as well as with proinsulin...

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Source

Identifiers

PMID: 21437630
DOI: 10.1007/s11033-011-0705-6

Genes

PCSK2
PCSK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of type 2 diabetes susceptibility genes (TCF7L2, SLC30A8, PCSK1 and PCSK2) and proinsulin conversion in a Chinese population.PMID 21437630Read ↗

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