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Article

TCF7L2 polymorphisms modulate proinsulin levels and beta-cell function in a British Europid population.

Diabetes - 1 Jul 2007

Loos Ruth J F, Franks Paul W, Francis Richard W, Barroso Inês, Gribble Fiona M, Savage David B, Ong Ken K, O'Rahilly Stephen, Wareham Nicholas J

Abstract excerpt

Rapidly accumulating evidence shows that common T-cell transcription factor (TCF)7L2 polymorphisms confer risk of type 2 diabetes through unknown mechanisms. We examined the association between four TCF7L2 single nucleotide polymorphisms (SNPs), including rs7903146, and measures of insulin sensit...

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Identifiers

PMID: 17416797
DOI: 10.2337/db07-0055
PMCID: PMC2668957

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17416797-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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TCF7L2 polymorphisms modulate proinsulin levels and beta-cell function in a British Europid population.PMID 17416797Read ↗

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