Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Common variants of transcription factor 7-like 2 (TCF7L2) are associated with reduced insulin secretion in women with polycystic ovary syndrome.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Aug 2012

Liu Bin, Lv Hui-Ming, Li Li-Nan, Xia Lei, Zhang Hong-Xiu, Zhang Ya-Juan, Lei Lei

Abstract excerpt

Common variants of the transcription factor 7-like 2 (TCF7L2) gene were identified as one of the few genetic polymorphisms with powerful effects on the risk of type 2 diabetes (T2D). Given the genetic overlap between polycystic ovary syndrome (PCOS) and T2D, the present study was undertaken to investigate whether the TCF7L2 variants are also associated with PCOS. We analyzed single nucleotide polymorphisms (SNPs)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hospitals, University
Share to Hyperglycemia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Infertility, Female

Share to Insulin

Share to Insulin Resistance

Share to Insulin Secretion

Share to Polycystic Ovary Syndrome

Share to Transcription Factor 7-Like 2 Protein

Source

Identifiers

PMID: 22296403
DOI: 10.3109/09513590.2011.650755

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Common variants of transcription factor 7-like 2 (TCF7L2) are associated with reduced insulin secretion in women with polycystic ovary syndrome.PMID 22296403Read ↗

Evidence for association between polycystic ovary syndrome (PCOS) and TCF7L2 and glucose intolerance in women with PCOS and TCF7L2.Semantic proximity Read ↗

Association of TCF7L2 genetic variants rs12255372 and rs7903146 with the polycystic ovary syndrome risk: systemic review and meta-analysis.Semantic proximity Read ↗

Transcription Factor-7-Like 2 Gene Variants Affect the Metabolic Phenotypes of Polycystic Ovary Syndrome.Semantic proximity Read ↗

The correlation between transcription factor 7-like 2 gene polymorphisms and susceptibility of gestational diabetes mellitus in the population of central China: A case-control study.Semantic proximity Read ↗

Genetic variants of cyclin-dependent kinase 5 regulatory subunit associated protein 1-like 1 and transcription factor 7-like 2 are not associated with polycystic ovary syndrome in Chinese women.Semantic proximity Read ↗

Genetic Association of Transcription Factor 7-Like-2 rs7903146 Polymorphism With Type 2 Diabetes MellitusSemantic proximity Read ↗

Disparate genetic influences on polycystic ovary syndrome (PCOS) and type 2 diabetes revealed by a lack of association between common variants within the TCF7L2 gene and PCOS.Semantic proximity Read ↗

Relationships between TCF7L2 genetic polymorphisms and polycystic ovary syndrome risk: a meta-analysis.Semantic proximity Read ↗

Genetic variants of TCF7L2 are associated with insulin resistance and related metabolic phenotypes in Taiwanese adolescents and Caucasian young adults.Semantic proximity Read ↗

Common variants in the TCF7L2 gene are strongly associated with type 2 diabetes mellitus in the Indian population.Semantic proximity Read ↗

Polymorphism in the Transcription Factor 7-Like 2 (TCF7L2) Gene Is Associated With Reduced Insulin Secretion in Nondiabetic WomenSemantic proximity Read ↗

Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.