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Article

Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians.

Diabetes - 1 Aug 2008

Ng Maggie C Y, Park Kyong Soo, Oh Bermseok, Tam Claudia H T, Cho Young Min, Shin Hyoung Doo, Lam Vincent K L, Ma Ronald C W, So Wing Yee, Cho Yoon Shin, Kim Hyung-Lae, Lee Hong Kyu, Chan Juliana C N, Cho Nam H

Abstract excerpt

OBJECTIVE: Recent genome-wide association studies have identified six novel genes for type 2 diabetes and obesity and confirmed TCF7L2 as the major type 2 diabetes gene to date in Europeans. However, the implications of these genes in Asians are unclear. RESEARCH DESIGN AND METHODS: We studied 13 associated single nucleotide polymorphisms from these genes in 3,041 patients with type 2 diabetes and 3,678 control...

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Identifiers

PMID: 18469204
DOI: 10.2337/db07-1583
PMCID: PMC2494677

Genes

FTO
CDKAL1
HHEX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Implication of genetic variants near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in type 2 diabetes and obesity in 6,719 Asians.PMID 18469204Read ↗

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Association between polymorphisms in SLC30A8, HHEX, CDKN2A/B, IGF2BP2, FTO, WFS1, CDKAL1, KCNQ1 and type 2 diabetes in the Korean population.Semantic proximity Read ↗

Investigation of type 2 diabetes risk alleles support CDKN2A/B, CDKAL1, and TCF7L2 as susceptibility genes in a Han Chinese cohort.Semantic proximity Read ↗

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