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Association of common variants of TCF7L2 and PCSK2 with gestational diabetes mellitus in West Bengal, India.

Nucleosides, nucleotides & nucleic acids - 1 Jan 2024

Basu Jayita, Mukherjee Ruchira, Sahu Pooja, Datta Chhanda, Chowdhury Subhankar, Mandal Debasmita, Ghosh Amlan

Abstract excerpt

The genetic etiology of gestational diabetes mellitus (GDM) was suggested to overlap with type-2 diabetes(T2D). Transcription factor 7-like 2 (TCF7L2) and Proprotein Convertase Subtilisin/Kexin type 2 (PCSK2) are T2D susceptibility genes of the insulin synthesis/processing pathway. We analyzed associations of TCF7L2 and PCSK2 variants with GDM risk and evaluated their potential impact on impaired insulin...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37610142
DOI: 10.1080/15257770.2023.2248201

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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