TCF7L2 genetic variants and progression to diabetes in the Chinese population: pleiotropic effects on insulin secretion and insulin resistance.

doi:10.1007/s00109-009-0542-4

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Article

TCF7L2 genetic variants and progression to diabetes in the Chinese population: pleiotropic effects on insulin secretion and insulin resistance.

Journal of molecular medicine (Berlin, Germany) - 1 Feb 2010

Chang Yi-Cheng, Chiu Yen-Feng, Ho Larry Low-Tone, Ting Chih-Tai, Shih Kuang-Chung, Curb J David, Chen Yii-Der Ida, Li Hung-Yuan, Chuang Lee-Ming

Abstract excerpt

TCF7L2 genetic variants were associated with progression to type 2 diabetes in Europeans. However, the role of TCF7L2 in type 2 diabetes remained uncertain in Chinese. Seventeen tag single nucleotide polymorphisms were genotyped in 1,094 subjects of Chinese origin from the Stanford Asia-Pacific Program for Hypertension and Insulin Resistance family study. At baseline, the rs7903146 T allele in the exon 4 linkage...

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PMID: 19806338
DOI: 10.1007/s00109-009-0542-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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