Article
[Effect of point substitutions in the MnSOD, GPX1, and GSTP1 genes on the risk of familial and sporadic breast cancers in residents of the Altaĭ region of the Russian Federation].
Genetika - 1 Dec 2010
Ermolenko N A, Boiarskikh U A, Sushko A G, Voronina E N, Selezneva I A, Sinkina T V, Lazarev A F, Petrova V D, Filipenko M L
Abstract excerpt
The frequencies of the polymorphic gene variants MnSOD Ala9Val, GPX1 Pro198Leu, and GSTP1 Ile105 Val were estimated in female residents of Altai krai with breast cancer. The frequency distributions of the genotypes for all genes studied in both patients and control subjects fit the Hardy-Weinberg equilibrium. The estimated frequencies of the genotypes for the studied genes in the control group did not differ from...
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