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Genetic polymorphism of manganese superoxide dismutase (MnSOD) and breast cancer susceptibility.

Cell biochemistry and function - 1 Jan 2000

Kocabaş Neslihan Aygün, Sardaş Semra, Cholerton Suzanne, Daly Ann K, Elhan Atilla H, Karakaya Ali Esat

Abstract excerpt

Within mitochondria, manganese superoxide dismutase (MnSOD) provides a major defence against oxidative damage by reactive oxygen species (ROS). An alanine-9valine (Ala-9Val) polymorphism in the mitochondrial targeting sequence of MnSOD has been described and has recently been associated with risk of human breast cancer. Our present case-control study was performed to explore the association between MnSOD genetic...

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PMID: 15386537
DOI: 10.1002/cbf.1128

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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