Article
Associations between SNPs within antioxidant genes and the risk of prostate cancer in the Siberian region of Russia.
Pathology oncology research : POR - 1 Jul 2014
Oskina N A, Еrmolenko N A, Boyarskih U A, Lazarev A F, Petrova V D, Ganov D I, Tonacheva O G, Lifschitz G I, Filipenko M L
Abstract excerpt
In the present study we investigated the association of a number of polymorphic changes in antioxidant system genes (SNPs rs1050450 in the GPX1 gene, rs1695 and rs1138272 in the GSTP1 gene and rs4880 in the MnSOD gene) with the risk of prostate cancer. The association of disease stage and PSA levels with specific genotypes was also analyzed. A study was conducted with the participation of 736 Russian men. We...
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