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Article

Modeling of environmental and genetic interactions with AMBROSIA, an information-theoretic model synthesis method.

Heredity - 1 Oct 2011

Chanda P, Zhang A, Ramanathan M

Abstract excerpt

To develop a model synthesis method for parsimoniously modeling gene-environmental interactions (GEI) associated with clinical outcomes and phenotypes. The AMBROSIA model synthesis approach utilizes the k-way interaction information (KWII), an information-theoretic metric capable of identifying variable combinations associated with GEI. For model synthesis, AMBROSIA considers relevance of combinations to the...

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Identifiers

PMID: 21427755
DOI: 10.1038/hdy.2011.18
PMCID: PMC3182499

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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