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Article

The C2 domains of synaptotagmin--partners in exocytosis.

Trends in biochemical sciences - 1 Mar 2004

Bai Jihong, Chapman Edwin R

Abstract excerpt

Rapid signaling between neurons relies on the Ca(2+)-triggered exocytosis of neurotransmitters. Release is mediated by 'kiss-and-run' or complete fusion of secretory organelles with the plasma membrane. Current models indicate that exocytosis is regulated by synaptotagmin I (syt) and mediated by SNARE (soluble NSF-attachment protein receptor) proteins. Syt senses Ca(2+) via two conserved motifs, C2A and C2B. C2B...

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Source

Identifiers

PMID: 15003272
DOI: 10.1016/j.tibs.2004.01.008

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NSF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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