Article
SHN-1, a Shank homologue in C. elegans, affects defecation rhythm via the inositol-1,4,5-trisphosphate receptor.
FEBS letters - 12 Mar 2004
Jee Changhoon, Lee Jungsoo, Lee Jin Il, Lee Won Hae, Park Byung-Jae, Yu Jae-Ran, Park Eunhye, Kim Eunjoon, Ahnn Joohong
Abstract excerpt
Protein localization in the postsynaptic density (PSD) of neurons is mediated by scaffolding proteins such as PSD-95 and Shank, which ensure proper function of receptors at the membrane. The Shank family of scaffolding proteins contain PDZ (PSD-95, Dlg, and ZO-1) domains and have been implicated in the localizations of many receptor proteins including glutamate receptors in mammals. We have identified and...
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