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Article

Association of angiotensin II type 1 receptor-associated protein gene polymorphism with increased mortality in septic shock.

Critical care medicine - 1 Jul 2011

Nakada Taka-aki, Russell James A, Boyd John H, McLaughlin Luke, Nakada Emiri, Thair Simone A, Hirasawa Hiroyuki, Oda Shigeto, Walley Keith R

Abstract excerpt

OBJECTIVE: Angiotensin II and its postreceptor signaling are crucial in regulating vasomotor tone. The objective of this study was to test the hypothesis that single nucleotide polymorphisms in angiotensin II pathway genes alter outcome of septic shock. DESIGN: Genetic association study and in vitro experiment. SETTING: Intensive care units at academic teaching centers. PATIENTS: Derivation and validation septic...

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PMID: 21423001
DOI: 10.1097/CCM.0b013e318218665a

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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