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Article

Leucyl/cystinyl aminopeptidase gene variants in septic shock.

Chest - 1 May 2011

Nakada Taka-Aki, Russell James A, Wellman Hugh, Boyd John H, Nakada Emiri, Thain Katherine R, Thair Simone A, Hirasawa Hiroyuki, Oda Shigeto, Walley Keith R

Abstract excerpt

BACKGROUND: Vasopressin is an essential peptide hormone regulating cardiovascular homeostasis and an adjunctive vasopressor therapy for septic shock. METHODS: We tested for association between single nucleotide polymorphisms (SNPs) in vasopressin pathway genes and altered outcome in derivation (n = 589) and replication (n = 616) cohorts of patients with septic shock. The primary outcome was 28-day mortality and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21330387
DOI: 10.1378/chest.10-2517

Genes

LNPEP
AVP
OXTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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