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Article

Genetic variants associated with sepsis-associated acute kidney injury.

PloS one - 1 Jan 2024

Douville Nicholas J, Bastarache Lisa, Bertucci-Richter Emily, Patil Snehal, Jewell Elizabeth S, Freundlich Robert E, Kertai Miklos D, Engoren Milo C

Abstract excerpt

BACKGROUND: Kidney dysfunction is a common complication in septic patients. Studies have identified numerous risk factors for sepsis-associated acute kidney injury (S-AKI), yet there is wide variability in the incidence even among patients with similar risk factors, suggesting the presence of additional uncharacterized risk factors, including genetic differences. The expansion of biobanks, advances in genotyping,...

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Acute Kidney Injury
Aged
Genetic Predisposition to Disease
Genetic Variation
Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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PMID: 39636799
DOI: 10.1371/journal.pone.0311318
PMCID: PMC11620412

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