Article
[The associations of polymorphism of N-acetyltransferase 2 gene is associated with antituberculosis drug-induced hepatotoxicity in tuberculosis patients].
Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] - 1 Jan 2011
An Hui-ru, Wu Xue-qiong, Wang Zhong-yuan, Liang Yan, Zhang Jun-xian
Abstract excerpt
OBJECTIVE: To study the possible relationship between polymorphic N-acetyltransferase 2 (NAT2) acetylator status and antituberculosis drug-induced hepatotoxicity and to elucidate the molecular mechanism of antituberculosis drug-induced hepatotoxicity. METHODS: Blood samples from 101 tuberculosis cases with antituberculosis drug-induced hepatotoxicity and from 107 tuberculosis without antituberculosis drug-induced...
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