Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Heterogeneous stocks and selective breeding in aging research.

ILAR journal - 1 Jan 2011

McClearn Gerald E, McCarter Roger J

Abstract excerpt

There are advantages and limitations to using genetically heterogeneous stocks and selective breeding procedures in gerontological and health span research. Animal models that address complex systems of aging involve constraint or manipulation of genetic diversity. They derive from levels of genetic analysis ranging from molecular to quantitative and are relevant to levels of causal hierarchy from base sequences...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Breeding
Share to Genetic Heterogeneity

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genotype

Share to Models, Animal

Source

Identifiers

PMID: 21411854
DOI: 10.1093/ilar.52.1.16

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Heterogeneous stocks and selective breeding in aging research.PMID 21411854Read ↗

Exotic mice as models for aging research: polemic and prospectus by R. Miller et al.Semantic proximity Read ↗

Genetic variability and rodent models of human aging.Semantic proximity Read ↗

The great evolutionary divide: two genomic systems biologies of aging.Semantic proximity Read ↗

Issues in the choice of genetic configuration for animal aging models.Semantic proximity Read ↗

Selecting animal models of human aging: inbred strains often exhibit less biological uniformity than F1 hybrids.Semantic proximity Read ↗

Pathobiology of aging rodents: inbred and hybrid models.Semantic proximity Read ↗

Exotic mice as models for aging research: polemic and prospectus.Semantic proximity Read ↗

The Jackson Laboratory Nathan Shock Center: impact of genetic diversity on aging.Semantic proximity Read ↗

Genes as gerontological variables: uniform genotypes.Semantic proximity Read ↗

Heterogeneous Stock Populations for Analysis of Complex Traits.Semantic proximity Read ↗

Genetic modulation of the senescent phenotype of Homo sapiens.Semantic proximity Read ↗

Contemporary human genetic strategies in aging research.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.