Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Jackson Laboratory Nathan Shock Center: impact of genetic diversity on aging.

GeroScience - 1 Oct 2021

Korstanje Ron, Peters Luanne L, Robinson Laura L, Krasinski Stephen D, Churchill Gary A

Abstract excerpt

Healthspan is a complex trait, influenced by many genes and environmental factors that accelerate or delay aging, reduce or increase disease risk, and extend or reduce lifespan. Thus, assessing the role of genetic variation in aging requires an experimental strategy capable of modeling the genetic and biological complexity of human populations. The goal of the The Jackson Laboratory Nathan Shock Center (JAX NSC)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Genetic Variation
Share to Laboratories

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Longevity

Source

Open in PubMed Open full text

Identifiers

PMID: 34297313
DOI: 10.1007/s11357-021-00421-2
PMCID: PMC8599562

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Jackson Laboratory Nathan Shock Center: impact of genetic diversity on aging.PMID 34297313Read ↗

Accessing Data Resources in the Mouse Phenome Database for Genetic Analysis of Murine Life Span and Health Span.Semantic proximity Read ↗

Mice as a Mammalian Model for Research on the Genetics of AgingSemantic proximity Read ↗

Into the Wild: A novel wild-derived inbred strain resource expands the genomic and phenotypic diversity of laboratory mouse models.Semantic proximity Read ↗

Into the Wild: A novel wild-derived inbred strain resource expands the genomic and phenotypic diversity of laboratory mouse modelsSemantic proximity Read ↗

Investigating trajectories of aging using high-dimensional phenotyping in mice.Semantic proximity Read ↗

Comparison of mice with accelerated aging caused by distinct mechanisms.Semantic proximity Read ↗

Out of the bottleneck: the Diversity Outcross and Collaborative Cross mouse populations in behavioral genetics research.Semantic proximity Read ↗

Study of Longitudinal Aging in Mice: Presentation of Experimental Techniques.Semantic proximity Read ↗

Genetic correlation-guided mega-analysis of DO mice provides mechanistic insight and candidate genes for age-related pathologies.Semantic proximity Read ↗

Mouse Models to Disentangle the Hallmarks of Human AgingSemantic proximity Read ↗

Which mouse multiparental population is right for your study? The Collaborative Cross inbred strains, their F1 hybrids, or the Diversity Outbred population.Semantic proximity Read ↗

Removing the cloak of invisibility: phenotyping the mouse.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.