Pathobiology of aging rodents: inbred and hybrid models.

Abstract excerpt

The definition of inbred strains of animals is provided, underscoring the homogeneity of the individuals in a strain, as well as the lack of allelic variation within each individual. Inbred animals present long-term reproducibility and relative stability, which facilitates experimentation over a long period of time. The derivations of several specific groups of inbred animals including coisogenic, congenic, and...

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