Pathobiology of aging rodents: inbred and hybrid models.

doi:10.1016/s0531-5565(96)00037-x

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Article

Pathobiology of aging rodents: inbred and hybrid models.

Experimental gerontology - 1 Jan 2000

Lipman R D

Abstract excerpt

The definition of inbred strains of animals is provided, underscoring the homogeneity of the individuals in a strain, as well as the lack of allelic variation within each individual. Inbred animals present long-term reproducibility and relative stability, which facilitates experimentation over a long period of time. The derivations of several specific groups of inbred animals including coisogenic, congenic, and...

Topics

Aging
Animals
Chromosome Mapping
Hybridization, Genetic
Mice
Mice, Inbred Strains
Mutation
Rats
Rats, Inbred Strains
Reproducibility of Results

Source

Open in PubMed

Identifiers

PMID: 9088918
DOI: 10.1016/s0531-5565(96)00037-x

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