Article
Genetic variability and rodent models of human aging.
Experimental gerontology - 1 Jan 1992
Phelan J P
Abstract excerpt
Inbred strains, outbred strains, and natural populations of rodents differ greatly in the amount and nature of the genetic variability they possess. Consequently, as models of human aging they vary with respect to the areas of research to which they are best suited. Inbred strains, in which all individuals are genetically identical, are best suited as models of specific disease processes and for manipulations...
Topics
- Aging
- Animals
- Disease Models, Animal
- Female
- Genetic Variation
- Inbreeding
- Male
- Mice
- Rats
