Article
Comparison of alpha beta and gamma delta expressing CD3+ acute lymphoblastic leukemias.
Nouvelle revue francaise d'hematologie - 1 Jan 1990
Macintyre E A, Salloum E, Sigaux F
Abstract excerpt
Analysis of 267 consecutive cases of acute lymphoblastic leukemias (ALL) showed that 67 (25%) of cases were of T cell lineage and that 21/67 (31%) expressed the CD3 antigen. Of 13 CD3+ T-ALLs, 7 expressed gamma delta and 6 alpha beta. Comparison of these 2 groups showed differences in clinical and immunophenotypic parameters. The patterns of rearrangement of TCR gamma and TCR delta genes and their junctional...
Topics
- Adolescent
- Antigens, CD
- Antigens, Differentiation, T-Lymphocyte
- Base Sequence
- CD3 Complex
- Child
- Child, Preschool
- Female
- Gene Rearrangement, T-Lymphocyte
- Humans
- Leukemia-Lymphoma, Adult T-Cell
