Article
Detection of T cell receptor delta gene rearrangements in childhood B and T lineage acute lymphoblastic leukaemia by southern blot and PCR: technical comparison of two methods of analysis.
Clinical and laboratory haematology - 1 Oct 2000
Valetto A, Di Martino D, Scuderi F, Lanza T, Lanciotti M, Bottini F, Dini G
Abstract excerpt
Molecular analysis of antigen receptor genes (Ig and TCR) has been useful for clonal studies in acute lymphoblastic leukaemia (ALL) patients. Rearrangements of these genes can be used to track the persistence of the leukaemic clone during the therapy. The purpose of our study was to analyse the percentage and the pattern of the rearrangements at the TCR D locus in a series of ALL patients, comparing the results...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.