Repertoire analysis of human peripheral blood lymphocytes using a human V δ 3 region-specific monoclonal antibody. Characterization of dual T cell receptor (TCR) δ-chain expressors and αβ T cells expressing V δ 3J α C α-encoded TCR chains

Abstract excerpt

V delta 3 usage and combinatorial expression of V gamma and V delta regions was studied on peripheral T cells with a novel V delta 3-specific mAb (p11.10b), generated against a soluble V gamma 9V delta 3 TCR. V delta 3+ cells represented the vast majority of V delta 1/V delta 2- gamma delta T cells within peripheral blood and mucosal lymphocytes. No preferential V gamma region expression was noted within V delta...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to CAR-T cell therapy research
• Share to Immune Cell Function and Interaction