Article
Alterations in the expression pattern of TCR zeta chain in T cells from patients with hematological diseases.
Hematology (Amsterdam, Netherlands) - 1 Oct 2008
Li Yangqiu
Abstract excerpt
The TCR zeta chain, a component of the T cell receptor (TCR)/CD3 complex, plays a significant role in the assembly of the receptor complex and in connecting antigen recognition to the intracellular signal transduction apparatus. Recently, studies have demonstrated altered expression and function of this signal transduction molecule in T cells from patients with hematological diseases. In this review, current...
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