Article
Adenovirus early region 3 promoter regulation by E1A/E1B is independent of alterations in DNA binding and gene activation of CREB/ATF and AP1.
Journal of virology - 1 May 1990
Kornuc M, Kliewer S, Garcia J, Harrich D, Li C, Gaynor R
Abstract excerpt
Transcription of the adenovirus early region 3 promoter is strongly induced by the adenovirus E1A protein. Previous DNase I footprinting has indicated that four regions in this promoter serve as binding sites for HeLa nuclear proteins. These include binding sites for NF-1 (site IV), AP1 (site III...
Topics
- Adenovirus Early Proteins
- Adenoviruses, Human
- Base Sequence
- Blotting, Northern
- Cell Nucleus
- Chloramphenicol O-Acetyltransferase
- Cyclic AMP Response Element-Binding Protein
- DNA-Binding Proteins
- Gene Expression Regulation, Viral
- HeLa Cells
- Humans
- Molecular Sequence Data
- Mutation