Article
The adenovirus EII early promoter has multiple EIA-sensitive elements, two of which function cooperatively in basal and virus-induced transcription.
Journal of virology - 1 Jun 1990
Manohar C F, Kratochvil J, Thimmapaya B
Abstract excerpt
The mechanism by which the adenovirus-encoded nuclear oncogene EIA activates transcription of several viral and host promoters is an important issue in the regulation of eucaryotic gene expression and virus-host cell interactions. Identification of cis-acting elements of the promoters and the cog...
Topics
- Adenovirus Early Proteins
- Adenoviruses, Human
- Base Sequence
- DNA-Binding Proteins
- Gene Expression Regulation, Viral
- HeLa Cells
- Humans
- Molecular Sequence Data
- Mutation
- Oncogene Proteins, Viral
- Oncogenes
- Promoter Regions, Genetic
- RNA, Messenger
- Restriction Mapping
- Trans-Activators
- Transcription, Genetic