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Article

Ribosomal RNA and protein mutants resistant to spectinomycin.

The EMBO journal - 1 Mar 1990

Bilgin N, Richter A A, Ehrenberg M, Dahlberg A E, Kurland C G

Abstract excerpt

We have compared the influence of spectinomycin (Spc) on individual partial reactions during the elongation phase of translation in vitro by wild-type and mutant ribosomes. The data show that the antibiotic specifically inhibits the elongation factor G (EF-G) cycle supported by wild-type ribosome...

Topics

Escherichia coli
Kinetics
Mathematics
Mutation
Peptide Elongation Factor G
Peptide Elongation Factor Tu
Peptide Elongation Factors
RNA, Ribosomal
Ribosomal Proteins
Ribosomes
Spectinomycin

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Identifiers

PMID: 2138078
DOI: 10.1002/j.1460-2075.1990.tb08167.x
PMCID: PMC551729

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2138078-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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