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Article

Phenotypic Suppression of Streptomycin Resistance by Mutations in Multiple Components of the Translation Apparatus.

Journal of bacteriology - 1 Sept 2015

Carr Jennifer F, Lee Hannah J, Jaspers Joshua B, Dahlberg Albert E, Jogl Gerwald, Gregory Steven T

Abstract excerpt

UNLABELLED: The bacterial ribosome and its associated translation factors are frequent targets of antibiotics, and antibiotic resistance mutations have been found in a number of these components. Such mutations can potentially interact with one another in unpredictable ways, including the phenotypic suppression of one mutation by another. These phenotypic interactions can provide evidence of long-range functional...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drug Resistance, Bacterial

Share to Gene Expression Regulation, Bacterial

Share to Ribosomes

Share to Selection, Genetic

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Share to Thermus thermophilus

Source

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Identifiers

PMID: 26148717
DOI: 10.1128/JB.00219-15
PMCID: PMC4542173

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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