Article
Thyroid-stimulating hormone, 5-HTTLPR genotype, and antidepressant response in depressed women.
Psychiatric genetics - 1 Oct 2011
Gressier Florence, Trabado Séverine, Verstuyft Céline, Bouaziz Elodie, Hardy Patrick, Fève Bruno, Becquemont Laurent, Corruble Emmanuelle
Abstract excerpt
Basal serum thyroid-stimulating hormone (TSH) levels may predict antidepressant efficacy in patients with major depressive episodes (MDE), but data are inconsistent. As the SS genotype of the 5-HTTLPR polymorphism has been associated with a lower antidepressant efficacy in women with MDE, we aimed at assessing the relationship between normal basal TSH, 5-HTTLPR, and antidepressant efficacy in women. A total of 71...
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