Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

5-HTTLPR modulates antidepressant efficacy in depressed women.

Psychiatric genetics - 1 Aug 2009

Gressier Florence, Bouaziz Elodie, Verstuyft Céline, Hardy Patrick, Becquemont Laurent, Corruble Emmanuelle

Abstract excerpt

BACKGROUND: As compared with the long variant (L), the short variant (S) of the functional polymorphic region of the serotonin transporter gene (5-HTTLPR) has been associated with a lower antidepressant efficacy in major depression, but some replication studies have evidenced contradictory results. Sex differences may explain these contradictory results. METHODS: One hundred and three inpatients (74 women and 29...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Antidepressive Agents
Share to Depressive Disorder

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Pharmacogenetics

Share to Protein Isoforms

Share to Serotonin Plasma Membrane Transport Proteins

Share to Treatment Outcome

Source

Identifiers

PMID: 19451862
DOI: 10.1097/YPG.0b013e32832cef0d

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

5-HTTLPR modulates antidepressant efficacy in depressed women.PMID 19451862Read ↗

Antidepressant response and the serotonin transporter gene-linked polymorphic region.Semantic proximity Read ↗

Pharmacogenetics and the serotonin transporter in late-life depressionSemantic proximity Read ↗

Thyroid-stimulating hormone, 5-HTTLPR genotype, and antidepressant response in depressed women.Semantic proximity Read ↗

Meta-analysis of serotonin transporter gene promoter polymorphism (5-HTTLPR) association with antidepressant efficacy.Semantic proximity Read ↗

Menopausal status could modulate the association between 5-HTTLPR and antidepressant efficacy in depressed women: a pilot study.Semantic proximity Read ↗

Serotonin transporter promoter gene polymorphism and long-term outcome of antidepressant treatmentSemantic proximity Read ↗

Moderation of antidepressant response by the serotonin transporter gene.Semantic proximity Read ↗

Effects of the serotonin transporter gene promoter polymorphism on mirtazapine and paroxetine efficacy and adverse events in geriatric major depression.Semantic proximity Read ↗

The serotonin transporter polymorphism, 5HTTLPR, is associated with a faster response time to sertraline in an elderly population with major depressive disorder.Semantic proximity Read ↗

The influence of 5-HTTLPR and STin2 polymorphisms in the serotonin transporter gene on treatment effect of selective serotonin reuptake inhibitors in depressive patients.Semantic proximity Read ↗

Serotonin transporter (5-HTT) promoter genotype may influence the prolactin response to clomipramine.Semantic proximity Read ↗

Association between serotonin transporter-linked polymorphic region and escitalopram antidepressant treatment response in Korean patients with major depressive disorder.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.