5-HTTLPR-rs25531 and Antidepressant Treatment Outcomes in Korean Patients with Major Depression.

doi:10.1055/a-1478-4574

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5-HTTLPR-rs25531 and Antidepressant Treatment Outcomes in Korean Patients with Major Depression.

Pharmacopsychiatry - 1 Nov 2021

Jang Yoo Jin, Lim Shinn-Won, Moon Young Kyung, Kim Su Yeon, Lee Hong, Kim Seonwoo, Kim Doh Kwan

Abstract excerpt

INTRODUCTION: Despite the ethnic differences in 5-HTTLPR (S allele relates to better antidepressant response in Korean and Japanese people, while L allele with better response in Caucasians), it is unclear whether 5-HTTLPR and its high expression locus rs25531 are interactively associated with antidepressant treatment outcome. We investigated the individual and interaction effects of these polymorphisms on...

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PMID: 33979867
DOI: 10.1055/a-1478-4574

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