Article
Menopausal status could modulate the association between 5-HTTLPR and antidepressant efficacy in depressed women: a pilot study.
Archives of women's mental health - 1 Dec 2014
Gressier Florence, Verstuyft Céline, Hardy Patrick, Becquemont Laurent, Corruble Emmanuelle
Abstract excerpt
The aim of this study was to evaluate the association between the functional polymorphic region of the serotonin transporter gene (5-HTTLPR) and antidepressant efficacy in menopausal and non-menopausal women. Since serotonergic system has been shown to be linked to estrogens, menopausal status of women may explain previous contradictory results on antidepressant efficacy in major depressive episode related to...
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